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CAS:84605-18-5
Molecular Formula:C30H50O5
Main Functions
Telomerase Activation:
Cycloastragenol is currently the only reported telomerase activator in natural products. By increasing telomerase activity, it can delay the shortening of telomeres, which are structures at the end of chromosomes that play a crucial role in maintaining genomic stability and cellular longevity.
Anti-Aging Effects:
By activating telomerase and delaying telomere shortening, cycloastragenol exhibits anti-aging effects. It can potentially extend the lifespan of cells and slow down the aging process.
Anti-Apoptotic and Anti-Fibrotic Properties:
Cycloastragenol has been shown to have anti-apoptotic and anti-fibrotic effects, which means it can protect cells from programmed cell death and reduce fibrosis, a condition characterized by excessive tissue scarring.
Immunomodulatory Effects:
It can regulate the immune system, enhancing the proliferation and activity of immune cells such as T-cells, which are crucial for fighting infections and maintaining immune homeostasis.
Wound Healing and Cell Proliferation:
Cycloastragenol promotes wound healing and cell proliferation, which are essential for tissue repair and regeneration.
Antioxidant and Anti-Inflammatory Activities:
It possesses antioxidant and anti-inflammatory properties, which help protect cells from oxidative stress and inflammation, two major contributors to cellular damage and aging.
Applications
Nutritional Supplements:
Due to its anti-aging and immunomodulatory effects, cycloastragenol is often used as an ingredient in nutritional supplements aimed at improving overall health and well-being.
Cosmetics:
Its anti-aging properties make it a valuable ingredient in cosmetics, where it can help reduce the appearance of fine lines and wrinkles.
Pharmaceutical Development:
Based on its diverse pharmacological effects, cycloastragenol holds potential for the development of new pharmaceuticals for the treatment of age-related diseases and conditions such as osteoporosis, cardiovascular disease, and immune dysfunction.
Biomedical Research:
Cycloastragenol is also used in biomedical research to study the mechanisms of aging, telomerase activity, and cellular senescence.
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