+86-15212299029
- All
- Product Name
- Product Keyword
- Product Model
- Product Summary
- Product Description
- Multi Field Search
Views: 220 Author: tcchems Publish Time: 2025-08-06 Origin: Site
Content Menu
● What is Magnesium Ascorbyl Phosphate?
● Applications in Food and Health Products
>> MAP in Skin Care and Topical Products
>> Emerging Roles and Research
● Safety Profile of Magnesium Ascorbyl Phosphate
● Efficacy of Magnesium Ascorbyl Phosphate
>> Skin Lightening and Anti-Aging
>> Stability and Bioavailability
>> Concentrations and Formulations
● Future Directions and Research
● Frequently Asked Questions (FAQs)
Magnesium Ascorbyl Phosphate (MAP) is a stable, water-soluble derivative of vitamin C (ascorbic acid) that is widely used both in topical skin care formulations and increasingly explored in food and health products. This article delves into the chemistry, applications, safety profile, and efficacy of MAP, providing a comprehensive overview of its roles and benefits in health and nutrition.
Magnesium Ascorbyl Phosphate is a magnesium salt of ascorbic acid-2-phosphate. It functions as a pro-vitamin C compound, releasing active vitamin C once metabolized. Unlike pure ascorbic acid, it boasts better stability—particularly against heat, light, and oxidation—and improved skin penetration due to its water solubility. This makes MAP highly desirable in cosmetic and some ingestible products where vitamin C's potent antioxidant effects are desired but direct ascorbic acid might degrade too rapidly.
Chemically, MAP offers antioxidant and anti-inflammatory properties, aiding in scavenging free radicals and reducing oxidative stress in cells. It also supports collagen synthesis, an essential protein for skin and tissue repair.
Magnesium Ascorbyl Phosphate is found in food supplements as a stable vitamin C source. Vitamin C is an essential nutrient with roles in immune support, antioxidant defense, collagen production, and enzymatic functions. Due to its enhanced stability compared to ascorbic acid, MAP is favored in some formulations to provide longer shelf life and sustained vitamin C release.
MAP is extensively incorporated in topical formulations like creams, serums, and lotions for skin whitening, anti-aging, and repair benefits. Its antioxidant activity helps reduce the damaging effects of UV exposure and environmental pollutants. Studies have shown that MAP stimulates collagen production, improves skin hydration, and reduces hyperpigmentation by interfering with melanin synthesis.
Its stability allows products containing MAP to maintain efficacy over longer periods compared to formulations based on pure ascorbic acid.
Beyond traditional uses, research investigates MAP's delivery via novel carriers such as vesicles and ethosomes to enhance skin absorption and therapeutic effects with minimal irritation. Additionally, MAP's chelating capacity for metal ions may benefit formulations targeting oxidative damage prevention in cells.
Extensive studies reveal that Magnesium Ascorbyl Phosphate has a very low toxicity profile. It is generally regarded as safe for topical and oral use within recommended concentrations. Animal studies have displayed minimal irritation or sensitization reactions even at relatively high doses.
Inhalation and ingestion may cause mild irritation in rare cases, but no severe toxic effects have been documented. It is non-flammable, has low reactivity, and does not pose significant environmental hazards.
Clinical trials confirm MAP is well tolerated on human skin. One study combining 5% MAP with other key ingredients found it safe, with no significant adverse reactions reported. Its minimal potential for irritation compared to ascorbic acid makes it more suitable for sensitive skin types.
Even when applied in higher concentrations topically, MAP does not induce sensitization or significant erythema in most users.
MAP is not classified as a hazardous substance by occupational safety organizations, and regulatory bodies recognize it as a safe ingredient for cosmetic and food applications. Manufacturers handle MAP under standard safety and hygiene conditions, ensuring product purity and consumer safety.
MAP is an effective antioxidant. It neutralizes free radicals and reactive oxygen species that contribute to cellular damage, aging, and inflammation. This action underlies many of its health benefits, ranging from immune support in food supplements to skin protection in topical products.
One of MAP's hallmark benefits in cosmetics is its ability to lighten hyperpigmentation and age spots by inhibiting tyrosinase activity, the enzyme responsible for melanin production. Regular use improves skin brightness and tone.
MAP also promotes collagen synthesis, supporting skin elasticity and reducing fine lines and wrinkles, thereby contributing to an overall anti-aging effect.
Compared to ascorbic acid, MAP provides enhanced chemical stability, maintaining potency even in the presence of air and light, which typically degrade vitamin C. Its water solubility facilitates better product formulation and skin absorption.
Once applied or ingested, enzymatic processes convert MAP into active ascorbic acid, ensuring effective delivery of vitamin C to target tissues.
For topical use, MAP concentrations between 5% and 10% are common to achieve visible benefits without causing irritation. In oral supplements, dosage depends on the intended nutritional support and product design, with the compound serving as a vitamin C source with sustained release characteristics.
MAP should be stored in cool, dry places away from strong light to maintain efficacy. Products containing MAP are often formulated with stabilizers to further extend shelf life.
Side effects, if any, are typically mild and rare. Some individuals may experience minor redness or sensitivity when first using MAP-containing topical products, but these usually resolve as the skin adapts.
Ongoing studies aim to optimize MAP delivery in health and cosmetic products, exploring advanced encapsulation methods such as liposomes and ethosomes that improve penetration and controlled release. There is also growing interest in its role in systemic antioxidant therapies, wound healing, and as part of multifunctional formulations combining MAP with other bioactive compounds.
Q1: Is Magnesium Ascorbyl Phosphate safe to use on sensitive skin?
A1: Yes, MAP is generally well tolerated and less irritating than ascorbic acid, making it suitable for sensitive skin types when used at recommended concentrations.
Q2: How does Magnesium Ascorbyl Phosphate differ from regular vitamin C?
A2: MAP is a more stable, water-soluble derivative of vitamin C that converts into active ascorbic acid upon metabolism, providing enhanced stability and sustained efficacy in products.
Q3: Can Magnesium Ascorbyl Phosphate be taken orally as a vitamin C supplement?
A3: Yes, MAP can serve as a stable vitamin C source in oral supplements, though its primary widespread use is topical in cosmetics.
Q4: What concentration of MAP is effective in skincare products?
A4: Topical formulations typically use 5-10% MAP to balance efficacy and minimize the risk of irritation.
Q5: Are there any known side effects of Magnesium Ascorbyl Phosphate?
A5: Side effects are rare and usually mild, such as minor skin redness or irritation that often subsides with regular use.
[1] https://www.cir-safety.org/sites/default/files/Ascorbic%20Acid.pdf
[2] https://ecdn6.globalso.com/upload/p/568/source/2025-01/aogubio-msds-of-Magnesium-ascorbyl-phosphate-%E7%BB%B4%E7%94%9F%E7%B4%A0%E7%A3%B7%E9%85%B8%E9%85%AF%E9%95%81.pdf
[3] https://pmc.ncbi.nlm.nih.gov/articles/PMC11457776/
[4] https://www.sigmaaldrich.com/US/en/product/sigma/a8960
[5] https://pmc.ncbi.nlm.nih.gov/articles/PMC9040897/
[6] https://pubchem.ncbi.nlm.nih.gov/compound/71587428
[7] https://www.tandfonline.com/doi/abs/10.2147/CCID.S473224
[8] https://www.semanticscholar.org/topic/MAGNESIUM-ASCORBYL-PHOSPHATE/1694819
[9] https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2013.3103
[10] https://go.drugbank.com/salts/DBSALT001594
Hot Tags: China, Global, OEM, private label, manufacturers, factory, suppliers, manufacturing company
